Alcohol Intolerance: Symptoms, Causes, and Testing

People with an alcohol intolerance or sensitivity can start feeling sick after just a few sips of alcohol. If you’re one of the many people who feel hungover after just 1 drink, here’s what you need to know about alcohol intolerance. Alcohol flushing syndrome is a major sign of alcohol intolerance. Your face, neck and chest become warm and pink or red right after you drink alcohol. Alcoholic drinks high in sulphites and/or histamine include wine (red, white, rosé and sparkling), cider and beer.

Alcohol as an ingredient can also increase gut permeability, allowing toxins and bacteria to pass into the bloodstream, which can increase the likelihood of an intolerance forming. When it comes to allergies to any component of an alcoholic drink, you must never consume it. Research suggests that up to 10 percent of asthmatics are sensitive to sulphites, with the severity of reactions varying from mild to life-threatening. “The wheezing and nasal/sinus symptoms in particular are due to the release of sulphur dioxide gas causing airway irritation,” Dr Watts explains.

Why Am I Developing Alcohol Sensitivity?

If you have this variant, it causes your body to produce less active ALDH2. Aldehyde dehydrogenase (ALDH2) is an enzyme that your body uses to digest alcohol. It turns alcohol into acetic acid, a main component of vinegar, in your liver.

  • Symptoms of alcohol intolerance can make a person feel uncomfortable.
  • If you drink alcohol while taking these medications, you can experience alcohol intolerance.
  • The symptoms of alcohol allergy can be very similar to alcohol intolerance.
  • It’s also found in many foods and beverages, especially fermented products.
  • Although genetics can play a role, it is rarely the underlying factor.

The symptoms are caused because the body’s immune system becomes overactive and attacks something found in the alcohol. Alcohol intolerance is something that causes immediate, uncomfortable reactions whenever you drink any kind of alcohol. The most common symptoms include flushing red skin, inflammation, a stuffy nose or watery eyes. Your doctor can give you medications to lessen the symptoms of alcohol intolerance, such as anti-inflammatory medicines for pain. However, many medicines are not supposed to be used with alcohol. Additionally, medications only help mask symptoms and do not help with the underlying problem.

What are symptoms of alcohol intolerance?

The acetaldehyde that builds up and causes alcohol intolerance is a major contributing factor in hangovers. While hangovers are often not exclusively due to high acetaldehyde levels, they play a large role. Someone who has alcohol intolerance is more likely to have a hangover, and hangovers that do occur will be more severe than they would have been otherwise. When doctors diagnose alcohol intolerance, they typically use the immediate symptoms it causes. These symptoms are almost always present with alcohol intolerance. There are, however, other symptoms that may occur as delayed symptoms of alcohol intolerance.

However, these symptoms can also be caused by other conditions, so it’s important to seek a medical diagnosis and take an alcohol sensitivity test to be sure. In fact, there can be many reasons why people are intolerant to alcoholic drinks, and most don’t have anything to do with the ethanol itself. What we understand as a ‘hangover’ is made up of a particular set of symptoms – usually a thumping headache, nausea, intense thirst, tiredness and brain fog. This is all happens as a result of drinking alcohol, or more specifically, the series of bodily processes it sets in motion. Having an alcohol intolerance is a genetic condition that means your body can’t process alcohol easily. With this condition, you have an inactive or less-active form of the chemical that breaks down alcohol in your body.

Acute alcohol sensitivity

If you develop symptoms after drinking alcohol, make an appointment with your doctor. Depending on your symptoms, they might refer you to an allergist for testing and treatment. An allergist is a special type of doctor that focuses on allergic conditions. People may also have an allergic reaction to specific ingredients in alcoholic drinks rather than the alcohol itself. Most people who have a reaction to alcohol aren’t allergic to it. They don’t have one of the active enzymes needed to process alcohol — alcohol dehydrogenase (ADH) or aldehyde dehydrogenase (ALDH).

signs of alcohol intolerance

The antibiotic metronidazole (Flagyl) can cause alcohol intolerance while being used. Another medicine called disulfiram (Antabuse) is actually designed to cause alcohol intolerance to help people stop drinking. These compounds are often added to beer and wine to limit the growth of yeast and act as a preservative.

Medical Professionals

There is no cure or treatment for alcohol intolerance unless it is due to medication use or a medical condition. For people who have alcohol intolerance due to a medication, stopping the medication will likely resolve the alcohol intolerance. If it is an inherited genetic condition, medical professionals are limited to providing ways to reduce the unpleasant symptoms of alcohol intolerance. In some cases, over-the-counter or prescribed medications might help alleviate symptoms. True alcohol allergy is thought to be rare, while alcohol intolerance is more common.

One study of 948 individuals found that 7.2% self-reported wine intolerance. An inherited metabolic disorder means you got this condition from your parents what causes alcohol intolerance — they each passed down a mutated (changed) gene that resulted in this disorder. Even if your parents don’t have the condition, they can pass it to you.